Exposomics is fundamentally shifting our ability to understand human health, disease, and effective interventions for treatment. This two-day symposium will bring together senior and junior research scientists interested in learning and sharing innovative tools that improve exposure data collection and other new methods in the field. The first day will focus on recent developments on data integration, analytical tools, and innovative exposure designs. Trainees and early investigators will have the opportunity to present their research in lightning talks followed by a moderated discussion. The second day will focus on the role of exposomics in the context of the COVID-19 pandemic and health disparities research.